procyclidine hydrochloride

Control of extrapyramidal symptoms Acute dystonias

Oral: 2.5–10 mg 3 times a day; maximum 60 mg dailyAcute dystonias: IM/IV: 5–10 mg

Molecular weight :323.9

%Protein binding :No data

%Excreted unchanged in urine : <5

Volume of distribution (L/kg) :1

half-life – normal/ESRD (hrs) :12/–

20 to 50 : Dose as in normal renal function

10 to 20 : Dose as in normal renal function

<10 : Dose as in normal renal function

CAPD :Unknown dialysability. Dose as in normal renal function

HD :Not dialysed. Dose as in normal renal function

HDF/high flux :Unknown dialysability. Dose as in normal renal function

CAV/VVHD :Unknown dialysability. Dose as in normal renal function

Potentially hazardous interactions with other drugs

None known

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IV, IM, oral

Bolus over 3–5 minutes

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